Agents Used in Antiretroviral Therapy

  • Authors: Philip Grant, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 9/10/19 (What's New)

Summary

  • Several approved antiretroviral agents are not recommended in current antiretroviral therapy guidelines and are not commonly used in clinical practice
  • In some settings patients may still be receiving these agents, either because they have been able to tolerate them for many years or because they are unable to receive recommended regimens because of contraindications, drug–drug interactions, hypersensitivity, or resistance
  • NRTIs
      DidanosineStavudine
        Zidovudine
        NNRTIs
          Delavirdine
            Nevirapine
            PIs
              Lopinavir/Ritonavir
                Fosamprenavir
                  Indinavir
                    Nelfinavir
                      Saquinavir
                        Tipranavir
                        Fusion Inhibitors
                          Enfuvirtide
                          Entry Inhibitors: CCR5 Antagonists
                            Maraviroc

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