Agents Used in Antiretroviral Therapy

  • Authors: Philip Grant, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 4/9/19 (What's New)

Summary

  • Indinavir in combination with antiretroviral agents is indicated for treatment of HIV infection, though it should not be used[FDA Indinavir]
  • Indinavir is dosed with food at 800 mg either 3 times daily or twice daily if coadministered with ritonavir 100 mg
  • Potential adverse effects include lipohypertrophy, kidney stones, renal failure, nausea, indirect hyperbilirubinemia, headache, and increased risk for myocardial infarction[FDA Indinavir; Worm 2010]

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