Agents Used in Antiretroviral Therapy

  • Authors: Philip Grant, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 4/9/19 (What's New)

Summary

  • Nelfinavir in combination with other antiretroviral agents is indicated for treatment of HIV infection, though with rare exceptions, its use should be discouraged
  • May be used for both treatment-naive and treatment-experienced patients[FDA Nelfinavir]
  • Rarely used PI because it is not effectively boosted by ritonavir and results in poorer virologic outcomes than ritonavir-boosted PIs[Walmsley 2002]

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