Agents Used in Antiretroviral Therapy

  • Authors: Philip Grant, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 4/9/19 (What's New)

Summary

  • Fusion inhibitors block fusion of HIV with host cell membrane
  • Currently only 1 fusion inhibitor approved by FDA: enfuvirtide (Table 16)
  • Enfuvirtide
    • Enfuvirtide, in combination with other antiretroviral agents, is indicated for treatment of HIV infection in treatment-experienced patients with evidence of HIV replication despite ongoing antiretroviral therapy[FDA Enfuvirtide]

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