Agents Used in Antiretroviral Therapy

  • Authors: Philip Grant, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 7/19/21 (What's New)

Summary

  • There are 6 available classes of antiretroviral therapy targeting several steps of HIV lifecycle (Figure 1)
    • Attachment
    • Coreceptor binding
    • Attachment; Coreceptor Binding; Fusion
      Uncoating and Reverse Transcription
        Integration
          Transcription, Translation, Assembly
            Budding and Maturation

            Action required

            Keywords: Initial Antiretroviral Therapy, Special Populations, Treatment Complications

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