Agents Used in Antiretroviral Therapy

  • Authors: Philip Grant, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 4/9/19 (What's New)

Summary

  • HIV integrase—a viral enzyme—catalyzes incorporation of double-stranded viral DNA into host DNA
  • After DNA strand transfer, host’s cellular DNA repair enzymes seal HIV viral DNA into host genome

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