Agents Used in Antiretroviral Therapy
Summary
- Etravirine is indicated in combination with other antiretroviral agents for treatment of HIV infection in treatment-experienced adult patients who have evidence of viral replication and resistance to an NNRTI and other antiretroviral agents[FDA Etravirine]
- Major advantage of etravirine compared with first-generation NNRTIs is its activity against many NNRTI-resistant variants
- K103N mutation alone has not been shown to compromise activity of etravirine
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