Timing of Initiation of First-line Antiretroviral Therapy
Summary
- ART in HIV-infected pregnant women dramatically reduces the risk of HIV transmission to their infants
- Treatment guidelines recommend use of ART in pregnant women regardless of CD4+ cell count to achieve undetectable plasma HIV-1 RNA levels (Management Guidelines)[DHHS Perinatal]
- There is mounting evidence that ART substantially reduces the risk of HIV transmission through breastfeeding[Thomas 2011; Chasela 2010]
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