Key Principles and Recommended Regimens for First-line Antiretroviral Therapy

  • Author: Paul E. Sax, MD (More Info)
  • Editors in Chief: Joseph J. Eron, Jr., MD; Daniel R. Kuritzkes, MD
  • Last Reviewed: 11/12/21 (What's New)


  • Patients should be referred to an HIV disease specialist for selection of first-line ART
  • Primary care physicians should be knowledgeable of recommended first-line antiretroviral regimens, drug–drug interactions, and adverse events associated with each agent
  • Primary care guidelines are available from the HIVMA of the IDSA (Management Guidelines)[Aberg 2014]

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