Key Principles and Recommended Regimens for First-line Antiretroviral Therapy

  • Author: Paul E. Sax, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 9/10/19 (What's New)

Summary

  • Treatment with abacavir may lead to a potentially life-threatening HSR
    • HSR occurs in 5% to 8% of patients treated with abacavir[FDA Abacavir]
    • Risk for HSR is strongly linked to the presence of the HLA-B*5701 allele[Mallal 2008]

Action required

Keywords: Cardiovascular Disease, Initial Antiretroviral Therapy, Renal Complications, Treatment Complications, Tropism

©2020 Clinical Care Options, LLC. All Rights Reserved.

The materials published via inPractice® reflect the views of the reviewers or authors of the material, not those of Clinical Care Options, LLC, the accredited provider, or the companies providing educational grants. The materials may discuss uses and dosages for therapeutic products that have not been approved by the United States Food and Drug Administration. A qualified healthcare professional should be consulted before using any therapeutic product discussed. Readers should verify all information and data before treating patients or using any therapies described in these materials.