Key Principles and Recommended Regimens for First-line Antiretroviral Therapy

Author: Paul E. Sax, MD (More Info)
Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
Last Reviewed: 5/20/20 (What's New)

Summary

Introduction

The goals of initial antiretroviral therapy include reduction of HIV-related morbidity and mortality, improved quality of life, restoration and preservation of immune function, control of HIV replication, and prevention of HIV transmission (Management Guidelines)^{[DHHS ART]}

Antiretroviral Treatment Guidelines for First-line Therapy in Adult Patients

In the United States and Europe, guidelines for initial antiretroviral therapy are issued by:
- US DHHS (Management Guidelines) (Table 1) (Table 2)^{[DHHS ART]}
- IAS-USA (Management Guidelines) (Table 1) (Table 2)^{[...
  
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