Optimizing Adherence to Antiretroviral Therapy
Summary
- Patterns and level of adherence associated with risk for viral rebound and resistance vary by viral fitness and antiretroviral drug and regimen characteristics
- DHHS, IAS-USA, and EACS recommend a number of coformulated, once-daily, and other simplified treatment options for initial ART[DHHS ART; IAS-USA ART; EACS ART]
- Simplified treatment regimens are effective, favored by patients and providers, and associated with better adherence,[Blaschke 2008; Ortiz 2008; Riddler 2008; van Dulmen 2007; Nachega 2014] yet, it may be difficult for some patients to maintain high levels of adherence even to simplified regimens
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Keywords: Adherence