Laboratory Assays in the Clinical Management of Antiretroviral Therapy

  • Author: Mark Holodniy, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 12/12/17 (What's New)

Introduction

  • Scientific discoveries relating to the structure and function of HIV-1 have led to the development of tests to monitor HIV-infected patients
  • Use of laboratory tests in managing HIV infection is an evolving practice
  • Consensus guidelines are available that recommend the most appropriate use of individual tests

The development of tests to monitor HIV-1 infection parallels discoveries of the structure and function of the virus. Physicians face the challenge of keeping abreast of scientific advances so that they can apply new knowledge in the care of their patients. This module briefly surveys the evolution of HIV-1 laboratory tests, the significance of surrogate markers in assessing HIV-1 infection, and guidelines and recommendations for the most appropriate use of individual tests.

CD4+ Cell Count Monitoring