Laboratory Assays in the Clinical Management of Antiretroviral Therapy

  • Author: Mark Holodniy, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 12/12/17 (What's New)


  • Multiple methods are available to detect and quantify HIV-1 viral load for assessment of risk of disease progression or response to antiretroviral therapy
  • US Department of Health and Human Services guidelines state that viral load testing can be used in patients with symptoms of acute HIV infection and in whom HIV antibody tests are negative or inconclusive (Management Guidelines) [DHHS ART]
  • HIV-1 viral load assays typically require up to 1 mL of plasma

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