Management of Treatment-Experienced Patients With HIV
Summary
- Clinical trial data defining the optimal management of patients experiencing treatment failure with first-line regimens consisting of NRTIs plus an INSTI are few
- An extrapolation of data on virologic failure of first-line NNRTI-based regimens[La Rosa 2016; Boyd 2013; Paton 2014] suggests that patients could be effectively treated with NRTIs plus a boosted PI in the setting of first-line INSTI failure
- In the absence of viral drug resistance, the emphasis should be on improving adherence to the original regimen
Action required
- Login now to access all of your entitled content
or - View additional options to gain access to this content