Management of Treatment-Experienced HIV-Infected Patients

  • Author: Eric S. Daar, MD (More Info)
  • Section Editor: Eric S. Daar, MD
  • Editors in Chief: Joseph J. Eron, Jr., MD; Daniel R. Kuritzkes, MD
  • Last Reviewed: 7/16/19 (What's New)


  • Few data are available on the optimal management of virologic failure with a first-line ritonavir-boosted PI regimen
  • A systematic review of multiple randomized, controlled trials of virologic failure with first-line ritonavir-boosted PI–based regimens showed that reinforced adherence and maintenance of the original regimen was as likely to result in virologic suppression as a modification in therapy[Zheng 2014]

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