Modifying Antiretroviral Therapy in Virologically Suppressed HIV-Infected Patients

  • Author: José R. Arribas, MD (More Info)
  • Section Editor: Eric S. Daar, MD
  • Editors in Chief: Joseph J. Eron, Jr., MD; Daniel R. Kuritzkes, MD
  • Last Reviewed: 10/18/21 (What's New)


  • In clinical trials of antiretroviral-naive patients, the proportion of patients achieving undetectable HIV-1 RNA was approximately 90%[Sax 2017]
  • Most patients will likely continue treatment with the same antiretroviral regimen for many years
  • For some patients there are often important, nonvirologic reasons to modify their antiretroviral regimen, such as drug intolerance or the need to simplify the regimen

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