Modifying Antiretroviral Therapy in Virologically Suppressed HIV-Infected Patients

  • Author: José R. Arribas, MD (More Info)
  • Section Editor: Eric S. Daar, MD
  • Editors in Chief: Joseph J. Eron, Jr., MD; Daniel R. Kuritzkes, MD
  • Last Reviewed: 10/18/21 (What's New)


  • First goal of regimen modification is to maintain undetectable HIV-1 RNA
  • There are multiple factors to consider before modifying a suppressive antiretroviral regimen including but not limited to:
    • Current and archived antiretroviral resistance mutations
  • Modifying an ART Regimen in a Patient With Current or Archived Resistance

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