Modifying Antiretroviral Therapy in Virologically Suppressed HIV-Infected Patients

  • Author: José R. Arribas, MD (More Info)
  • Section Editor: Eric S. Daar, MD
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 10/12/18 (What's New)

Summary

  • Results from the EASIER-ANRS 138 study[De Castro 2009] and other single-arm studies[Talbot 2009; Towner 2009] suggest that when substituting one antiretroviral agent with a low genetic barrier to resistance, such as enfuvirtide, for another, such as raltegravir, in virologically suppressed patients, the background regimen will most likely be potent enough to maintain virologic suppression

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