Metabolic Complications of HIV and Antiretroviral Therapy: Dyslipidemia, Insulin Resistance, and Cardiovascular Disease
Summary
- Screening for Dyslipidemia
- Baseline fasting lipids should be recorded for all HIV-infected patients at entry into care
- If no lipid abnormalities are present, repeat screening should be performed every 6-12 months, or more frequently if risk factors such as obesity, diabetes, fat redistribution, or a family history of dyslipidemia are present
- ACC/AHA guidelines on management of blood cholesterol recommend moderate- or high-intensity statin therapy in 4 target populations (Table 3) (Management Guidelines)[ACC/AHA 2013]
- Role and Limitations of Lifestyle Modifications
- Fibrates
- Switching NRTIs
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