Metabolic Complications of HIV and Antiretroviral Therapy: Dyslipidemia, Insulin Resistance, and Cardiovascular Disease

  • Authors: Judith S. Currier, MD, MSc; Risa Hoffman, MD, MPH (More Info)
  • Editors in Chief: Joseph J. Eron, Jr., MD; Daniel R. Kuritzkes, MD
  • Last Reviewed: 10/10/18 (What's New)

Summary

  • Metabolic syndrome is an important risk factor for cardiovascular disease in the general population, regardless of LDL value
  • Data from an HIV-infected cohort suggest the presence of metabolic syndrome is not a better predictor of cardiovascular disease than the individual components of the syndrome[Worm 2009]
  • Incidence of metabolic syndrome following ART initiation has been reported to range from 12-14 cases/100 patient-years[Palacios 2007; Wand 2007]

Action required

Keywords: Cardiovascular Disease, Diabetes, Dyslipidemia, Insulin Resistance, Treatment Complications

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