Metabolic Complications of HIV and Antiretroviral Therapy: Dyslipidemia, Insulin Resistance, and Cardiovascular Disease

  • Authors: Judith S. Currier, MD, MSc; Risa Hoffman, MD, MPH (More Info)
  • Editors in Chief: Joseph J. Eron, Jr., MD; Daniel R. Kuritzkes, MD
  • Last Reviewed: 10/10/18 (What's New)

Summary

  • Lifestyle modification is critical for the management of glucose disorders in patients with HIV[Knowler 2002]
  • Role of exacerbating medications in patients with glucose abnormalities should be reviewed, with discontinuation or substitution where feasible
  • Studies support the use of metformin for abnormal glucose metabolism in the absence of definite diabetes in HIV-infected patients
    • Treatment of Abnormal Glucose Metabolism With Metformin
      Treatment of Abnormal Glucose Metabolism With Thiazolidinediones
        Treatment of Abnormal Glucose Metabolism With Sulfonylureas, Meglitinides, GLP-1 Receptor Agonists, Gliptins, and Gliflozins
          Treatment of Abnormal Glucose Metabolism by Modifying Antiretroviral Therapy

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          Keywords: Diabetes, Insulin Resistance, Treatment Complications

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