Management of Bone Disease and Body Composition Changes

  • Author: Donald P. Kotler, MD (More Info)
  • Section Editor: Eric S. Daar, MD
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 5/7/18 (What's New)


  • Longitudinal measurements of BMI and circumference of waist, hip, thigh, and midarm were performed in 661 HIV-infected men and 392 non–HIV-infected men enrolled in the Multicenter AIDS Cohort Study[Brown 2007]
  • Cumulative NRTI exposure was associated with a decrease in BMI and in circumferences of waist, hip, and thigh
    • Exposure to NNRTIs and PIs was not associated with a change in these parameters

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