Management of Bone Disease and Body Composition Changes

  • Author: Donald P. Kotler, MD (More Info)
  • Section Editor: Eric S. Daar, MD
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 5/7/18 (What's New)


  • Diet composition and avoidance of weight gain may limit visceral fat accumulation in HIV-infected patients[Lazzaretti 2012; Joy 2007]
  • Several studies have documented effects of lifestyle changes on central fat[Roubenoff 1999; Fitch 2006; Driscoll 2004; Dolan 2006]
    • 1 study demonstrated that a 12-week weight-loss program in obese, HIV-infected women resulted in loss of subcutaneous, rather than visceral fat, and there was no effect of weight loss on insulin sensitivity or other measures of metabolism[Engelson 2006]

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