Key Pharmacologic Principles and Drug-Drug Interactions in HIV Patient Care

  • Authors: Amanda H. Corbett, PharmD, BCPS, FCCP; Colin I. Sheffield, PharmD (More Info)
  • Section Editor: Eric S. Daar, MD
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 6/3/19 (What's New)


  • Acid suppression agents can interact with antiretrovirals, which may influence regimen selection in patients receiving these drugs concomitantly (Table 3)
  • Several antiretrovirals have critical interactions with these drugs; clinicians should ask patients specifically about use of over-the-counter medications; dosing adjustments may be needed
  • Antiretrovirals and AntacidsAtazanavir and Acid-Reducing Agents
      Fosamprenavir and Acid-Reducing Agents
        Other PIs and Acid-Reducing Agents
          Rilpivirine and Acid-Reducing Agents

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