Key Pharmacologic Principles and Drug-Drug Interactions in HIV Patient Care
Summary
- Caution should be advised when antacids are used with atazanavir (with or without ritonavir), fosamprenavir, or tipranavir/ritonavir
- Patients should be instructed to take the PI either 2 hours before or 1 hour after the antacid (Management Guidelines)[DHHS ART]
- Antacids should be administered at least 2 hours before or 4 hours after receiving rilpivirine,[FDA Rilpivirine] emtricitabine/rilpivirine/tenofovir DF,[FDA Emtricitabine/Rilpivirine/Tenofovir] or emtricitabine/rilpivirine/tenofovir AF[FDA Emtricitabine/Rilpivirine/TAF]
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Keywords: Drug-Drug Interactions, Pharmacokinetics