Key Pharmacologic Principles and Drug-Drug Interactions in HIV Patient Care
Summary
- Efavirenz-based ART is the recommended option for patients receiving rifampin-based TB regimen
- Nevirapine-based or etravirine-based regimens should not be coadministered with rifampin due to the potential for significant decreases in NNRTI concentrations[DHHS ART]
- Rilpivirine and emtricitabine/rilpivirine/tenofovir DF, emtricitabine/rilpivirine/tenofovir AF, and doravirine are contraindicated with rifampin[FDA Rilpivirine; FDA Emtricitabine/Rilpivirine/Tenofovir; FDA Emtricitabine/Rilpivirine/TAF; FDA Doravirine]
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