Key Pharmacologic Principles and Drug-Drug Interactions in HIV Patient Care
Summary
- Simvastatin and lovastatin are contraindicated in patients receiving boosted PIs[Fichtenbaum 2002]
- Atorvastatin should be avoided in patients receiving tipranavir/ritonavir and atazanavir/cobicistat
- Use cautiously with other PIs, starting at low doses and titrating carefully
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Keywords: Drug-Drug Interactions, Pharmacokinetics