Key Pharmacologic Principles and Drug-Drug Interactions in HIV Patient Care

  • Authors: Amanda H. Corbett, PharmD, BCPS, FCCP; Colin I. Sheffield, PharmD (More Info)
  • Section Editor: Eric S. Daar, MD
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 6/1/18 (What's New)

Summary

  • Isavuconazole has potential for drug interactions with PIs and NNRTIs[DHHS ART]
    • Exposure may be increased when used with PIs, and drug concentrations, response, and toxicity should all be monitored
    • Exposure may be decreased when used with NNRTIs, and dose adjustments may be necessary

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