Epidemiology of HIV Infection in the Developing World

  • Authors: Sunil Solomon, MBBS, PhD, MPH; Suniti Solomon, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 4/1/16 (What's New)

Summary

  • Circumcision has been shown to reduce risk of HIV acquisition by approximately 50% to 60%[Auvert 2005; Bailey 2007; Gray 2007; Gray 2012; Mehta 2013]
  • Also associated with reduced risk of HSV-2 acquisition,[Tobian 2009] a major cofactor for HIV transmission
  • Initiation of sexual intercourse before adequate healing from circumcision is associated with increased risk of HIV acquisition[Wawer 2009]

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