Overview of HIV Prevention

  • Author: Sharon L. Hillier, PhD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 9/4/20 (What's New)


  • Nonspecific microbicides are topical products designed to prevent sexual transmission of HIV through the vaginal or rectal route
  • No nonspecific microbicide has demonstrated any level of effectiveness in reducing HIV infection in women (Table 2)
    • In comparison, antiretroviral-containing products with high potency against HIV have a significant impact on HIV acquisition

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