The Approach to the Patient With HIV With Specific Symptom Complexes/Common Presentations

  • Author: Steven C. Johnson, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 10/31/21 (What's New)


  • Incidence of opportunistic diseases in patients with HIV has declined dramatically with the availability of effective ART[Buchacz 2016]
  • Disease manifestations occurring in persons with HIV today are frequently due to comorbid diseases or diseases common to the general population
  • Generating an accurate differential diagnosis requires understanding of the types of illnesses that can occur in persons living with HIV infection
  • Guidelines for preventing and treating opportunistic infections in patients with HIV, produced jointly by the CDC, the NIH, and the HIV Medicine Association of the IDSA, are available (Management Guidelines)[CDC OI]

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