The Approach to the Patient With HIV With Specific Symptom Complexes/Common Presentations

  • Author: Steven C. Johnson, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 10/31/21 (What's New)


  • Pancytopenia is relatively frequent in advanced HIV infection
    • May be a manifestation of bone marrow involvement with opportunistic infections and malignancies or due to the direct effects of HIV[Dhurve 2013]
  • Thrombotic thrombocytopenic purpura is a potentially fatal multisystem illness in HIV infection

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