The Approach to the Patient With HIV With Specific Symptom Complexes/Common Presentations

  • Author: Steven C. Johnson, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 10/31/21 (What's New)


  • Progressive immunodeficiency in untreated HIV infection puts the patient at risk for opportunistic infections and malignancies
  • Relationship Among Specific Opportunistic Infections and CD4+ Cell Counts
    • Most opportunistic infections occur at CD4+ cell counts < 200 cells/mm3
    • Cytomegalovirus retinitis and disseminated Mycobacterium avium complex disease typically occur at CD4+ cell counts < 50 cells/mm3
    Geographic Variance in Occurrence of Opportunistic Infections
      Presentations of Opportunistic Infections in the Current Era of Antiretroviral Therapy

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