Tuberculosis and Other Mycobacterial Infections

  • Authors: Richard E. Chaisson, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 3/30/17 (What's New)

Summary

  • MAC, which includes Mycobacterium avium and Mycobacterium intracellulare, are the most common nontuberculous mycobacteria to cause disease in humans[Guthertz 1989; Griffith 2007]
  • Most common forms of MAC are pulmonary disease in adults who are not infected with HIV, disseminated disease in people infected with HIV, and lymphadenitis in children or in adults infected with HIV with IRIS[Griffith 2007]
  • MAC pulmonary disease most often occurs in middle-aged men who have history of heavy smoking, alcohol consumption, and gastroesophageal reflux and in postmenopausal white women[Griffith 2007; Thomson 2007]

Action required