Tuberculosis and Other Mycobacterial Infections

  • Authors: Richard E. Chaisson, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 3/30/17 (What's New)


    Disseminated MAC
    • Diagnosis of disseminated MAC is usually made on the basis of clinical presentation, CD4+ cell count, and results of mycobacterial culture of sterile body tissue or fluid, including blood, lymph node, or bone marrow[DHHS Adult OI; MacGregor 2005; Stone 1994]
    Pulmonary Mycobacterium Avium Complex
    • Diagnosis of pulmonary MAC should be made after the exclusion of TB and other common lung diseases on the basis of pulmonary symptoms such as chronic cough and the following workup:
      • 3 or more sputum specimens for AFB smear and mycobacterial culture, chest radiograph, and/or high-resolution chest computed tomography scan[Griffith 2007]
    Mycobacterium Avium Complex Immune Reconstitution Inflammatory Syndrome

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