Tuberculosis and Other Mycobacterial Infections

  • Authors: Richard E. Chaisson, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 3/30/17 (What's New)

Summary

  • Treatment for MAC should include either azithromycin or clarithromycin and ethambutol (Table 17)[DHHS Adult OI; Griffith 2007]
    • Susceptibility testing to azithromycin or clarithromycin is recommended in all patients with MAC
    • Addition of a third or fourth agent should be considered for patients with increased risk of mortality or emergence of resistance, including patients with CD4+ cell counts < 50 cells/mm3, > 2 log10 CFU/mL blood, or absence of effective ART

    Action required

    Keywords: Drug-Drug Interactions, Mycobacterium avium Complex

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