inPractice® - Prevention/Prophylaxis for <i>Mycobacterium Avium Complex</i>

Tuberculosis and Other Mycobacterial Infections

Authors: Richard E. Chaisson, MD (More Info)
Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
Last Reviewed: 3/30/17 (What's New)

Summary

Active MAC disease should be excluded before initiation of prophylactic regimens
Patients infected with HIV with CD4+ cell counts < 50 cells/mm³ should receive primary prophylaxis against disseminated MAC with azithromycin, 1200 mg orally once weekly^{[DHHS Adult OI; Griffith 2007]}
- Azithromycin and clarithromycin are DHHS-preferred prophylactic agents^{[DHHS Adult OI]}

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Keywords: Mycobacterium avium Complex