Fungal Infections

  • Author: William G. Powderly, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 6/18/19 (What's New)

Summary

  • Fluconazole or itraconazole can reduce the frequency of primary cryptococcal disease in patients with CD4+ cell counts < 50 cells/mm3[Powderly 1995; McKinsey 1999]
  • Antifungal prophylaxis is not recommended in developed countries due to the infrequency of cryptococcal disease and benefits of effective ART

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