Fungal Infections

  • Author: William G. Powderly, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 6/18/19 (What's New)


  • Histoplasmosis typically presents as fever, fatigue, and weight loss
  • Respiratory symptoms and abnormal chest radiograph occur in approximately 50% of cases
  • Local or generalized lymphadenopathy, hepatosplenomegaly, gastrointestinal lesions, skin and oral ulcers, and an acute septic shock–like syndrome also occur[Wheat 1990]

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