Fungal Infections

  • Author: William G. Powderly, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 6/18/19 (What's New)

Summary

  • Invasive aspergillosis, most frequently caused by A fumigatus, is rare in patients with HIV[Herbrecht 2002]
  • Risk factors include neutropenia, use of corticosteroids, broad-spectrum antibacterial therapy, and previous pneumonia, especially P jiroveci pneumonia
  • Typically, patients have extremely low CD4+ cell counts (< 50 cells/mm3), a history of other AIDS-defining opportunistic infections and are not receiving ART[Holding 2000]

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