Parasitic Infections in HIV-Infected Patients

  • Authors: José M. Miró, MD, PhD; Miriam J. Álvarez-Martínez, MD, PhD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 4/1/16 (What's New)

Summary

  • Secondary prophylaxis should be administered to all patients who have completed initial therapy for toxoplasmic encephalitis (Table 4)[CDC OI; Panel 2008a]
  • Preferred regimen is pyrimethamine plus sulfadiazine plus leucovorin (folinic acid)
  • Prophylaxis can be discontinued if the patient’s CD4+ cell count increases to > 200 cells/mm3 with use of ART for > 6 months and HIV-1 RNA remains undetectable (Table 5)[CDC OI; Panel 2008a; Miro 2006]

Action required