Management of AIDS-Defining Cancers

  • Authors: David Aboulafia, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 4/9/18 (What's New)


  • PELs are rare HHV8-associated lymphomas that are typically of B-cell origin and arise as a late manifestation of HIV disease[Aboulafia 2004; Raez 1998; Chen 2007]
  • Lymphomatous effusions are exudates that contain high-grade, malignant HHV8-positive lymphoma cells, typically detected by immunostaining
  • Therapy involves a combination of ART, OI prophylaxis, and systemic polychemotherapy[Chen 2007]

Action required

Keywords: Cancer