Non–AIDS-Defining Cancers

  • Authors: David Aboulafia, MD; Liron Pantanowitz, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 12/12/16 (What's New)

Summary

  • Some reports show HCC outcomes in HIV-infected patients are similar to those in HIV-uninfected patients when active treatment is provided,[Cantarini 2009; Yopp 2012; Bräu 2007] whereas other reports suggest HCC outcomes are worse with vs without HIV infection[Bower 2014; Berretta 2011; Gramenzi 2013]
  • Factors that may predict shorter survival in HIV-infected patients with HCC[Bräu 2007]: symptomatic presentation, BCLC classification stage C or D, AST/ALT ratio of at least 2.0, and AFP level ≥ 400 ng/mL

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