Management of Hematologic Disorders

  • Author: David Aboulafia, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 4/1/16 (What's New)

Summary

  • Multiple drugs, including various antiretroviral drugs and drugs used to treat opportunistic infections, are major cause of neutropenia in HIV infection (Table 6)
  • Neutropenia may also result from infections that involve bone marrow infiltration
  • Functional neutrophil defects have been identified in patients with HIV infection, though clinical importance is uncertain[Ellis 1988; Valone 1984]

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