Hepatic Disease in HIV-Infected Patients
Introduction to Hepatic Disease
- Abnormal liver test results are seen in approximately 30% of HIV-infected patients[Crum-Cianflone 2010]
- HIV-infected patients diagnosed with potential causes of liver disease (Table 1) or exhibiting clinical signs of liver disease (Table 2) should undergo a comprehensive medical evaluation
Liver disease ranks as a serious cause of morbidity and mortality in HIV-infected persons whose HIV disease is effectively controlled with antiretroviral therapy.[Weber 2006] Abnormal liver test results are seen in nearly 30% of HIV-infected patients.[Crum-Cianflone 2010] Chronic infection with hepatitis C virus (HCV) or hepatitis B virus (HBV) represents the most significant cause of liver disease in HIV-infected persons (Table 1). The shared routes of transmission of HIV, HCV, and HBV help to explain this phenomenon.[...