Hepatic Disease in HIV-Infected Patients
Summary
- Treatment of HIV disease may ameliorate the development of chronic liver disease due to viral hepatitis[Shafran 2007] Incidence
- In randomized, controlled trials, the proportion of patients receiving combination ART who have grades 3 or 4 elevations in serum ALT or AST levels range from approximately 2% to 18%[Nuñez 2006]
- Ritonavir-boosted PIs have not been associated with higher rates of hepatotoxicity
- Mitochondrial Toxicity
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