Hepatic Disease in Patients With HIV

  • Author: Mark S. Sulkowski, MD (More Info)
  • Editors in Chief: Joseph J. Eron, Jr., MD; Daniel R. Kuritzkes, MD
  • Last Reviewed: 11/13/21 (What's New)


  • The comprehensive care of patients with HIV must consider chronic liver injury due to HBV, HCV, nonalcoholic fatty liver disease, alcoholic liver disease, and drug-induced liver injury[Sulkowski 2004]
  • Primary care physicians should be aware of the frequency with which hepatic disease occurs among patients with HIV and should be vigilant for clinical or laboratory signs of liver disease in this population
  • In most cases, treatment of viral or nonviral hepatic disease in the setting of HIV infection is complicated by the interaction of the different disease states as well as potential drug–drug interactions, necessitating referral to hepatology and infectious disease specialty care

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