Endocrine Disorders: Evaluation and Management

  • Author: Todd T. Brown, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 11/14/16 (What's New)


  • Common symptoms of overt hypothyroidism are insidious onset of fatigue, weakness, dry skin, cold intolerance, slowed mentation, constipation, hoarse voice, paresthesia, bradycardia, and delayed tendon reflex relaxation[Roberts 2004]
  • Prevalence of overt hypothyroidism in HIV-infected individuals has been estimated to be between 0% and 2.6%[Beltran 2003; Madeddu 2006; Grappin 2000; Collazos 2003]
  • Overt hypothyroidism is treated with levothyroxine, with the goal of maintaining TSH between 0.5 and 2.0 mU/L[Wartofsky 2005]

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