Endocrine Disorders: Evaluation and Management

  • Author: Todd T. Brown, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 11/14/16 (What's New)


  • Subclinical hyperthyroidism is defined by low TSH with normal T3 and free thyroxine and absence of thyrotoxicosis[Toft 2001]
  • Treatment with antithyroid drugs or radioiodine thyroid ablation should be considered if symptoms are present
  • Guidelines suggest treatment be considered for patients who have a TSH < 0.1 mU/L, are older than 60 years of age, or are at increased risk of heart disease, osteopenia, or osteoporosis (Management Guidelines)[Subclinical Thyroid Guidelines]

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